YAP Inhibition Promotes Endothelial Cell Differentiation from Pluripotent Stem Cell through EC Master Transcription Factor FLI1

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Scientists checked transcriptional profile by microarray and found Hippo pathway was changed and the activity of YAP decreased during mesoderm-mediated endothelial cell differentiation from human ESCs.
[Journal of Molecular and Cellular Cardiology]
AbstractGraphical Abstract