α1-Adrenergic Receptor Mediates Adipose-Derived Stem Cell Sheet-Induced Protection against Chronic Heart Failure after Myocardial Infarction in Rats

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Hypoxia increased α1-AR and vascular endothelial growth factor (VEGF) mRNA levels in adipose-derived stem cells. Norepinephrine further increased VEGF mRNA expression under hypoxia; this effect was abolished by doxazosin.
[Hypertension Research]
Abstract