Targeting Senescence-Like Fibroblasts Radiosensitizes Non-Small Cell Lung Cancer and Reduces Radiation-Induced Pulmonary Fibrosis

Scientists identified the senescence-like characteristics of cancer-associated fibroblasts (CAFs) after RT and clarify the formidable ability of senescence-like CAFs in promoting NSCLC cell proliferation and radioresistance through the JAK/STAT pathway.