STAT3-YAP/TAZ Signaling in Endothelial Cells Promotes Tumor Angiogenesis

Scientists studied the role of YAP/TAZ signaling in endothelial cells (ECs) in tumor angiogenesis and found that the expression of YAP/TAZ and downstream target genes in ECs correlated with tumor vascularization in human colorectal carcinomas and skin melanoma.