SYT8 Promotes Pancreatic Cancer Progression via the TNNI2/ERRα/SIRT1 Signaling Pathway

Synaptotagmin-8 (SYT8) is a membrane protein that regulates hormone secretion and neurotransmission, and its expression is positively regulated by the promoter of the insulin gene in pancreatic islet cells. Researchers identified a previously unknown role of SYT8 in altering tumor characteristics in pancreatic cancer.