Soluble CD137 Is a Novel Serum Marker of Liver Cirrhosis in Patients with Hepatitis C and Alcohol-Associated Disease Etiology

Serum soluble CD137 (sCD137) is associated with inflammatory states, and positively correlated with serum tumor necrosis factor in cirrhotic hepatitis C virus (HCV) patients following virus eradication. Researchers argued against a role of sCD137 in HCV infection and suggested a function of sCD137 in liver cirrhosis.