Comparable Anti-CMV Responses of Transplant Donor and Third-Party CMV-Specific T Cells for Treatment of CMV Infection after Allogeneic Stem Cell Transplantation

The in vivo recovery of cytomegalovirus (CMV)-specific immunity after CMV-cytotoxic T lymphocytes (CTL) infusion was comparable in two groups. A detailed analysis of the source of recovered CMV-CTLs showed the proliferation and expansion of graft-derived endogenous CMV-CTLs in both groups.