Antineoplastic Effects of Erufosine on Small Cell and Non-Small Cell Lung Cancer Cells through Induction of Apoptosis and Cell Cycle Arrest

The effects of ErPC3 in NSCLC cell line A549 and SCLC cell line DMS 114 in terms of cell viability, induction of apoptosis, cell cycle phase distribution, gene and protein expression levels, and migration capacity were investigated. 25 µM ErPC3 exhibited dose-dependent cytotoxicity against in both cancer cells.