Pterostilbene Downregulates BCR/ABL and Induces Apoptosis of T315I-Mutated BCR/ABL-Positive Leukemic Cells

Scientists examined the antileukemic effects of pterostilbene, a natural methylated polyphenol analog of resveratrol that is predominantly found in berries and nuts, using various human and murine leukemic cells, as well as bone marrow samples obtained from patients with leukemia.