Beneficial Effects of Citrulline Enteral Administration on Sepsis-Induced T Cell Mitochondrial Dysfunction

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Scientists demonstrated that citrulline administration was more efficient than arginine in increasing arginine plasma levels and restoring T cell mitochondrial function and proliferation while reducing sepsis-induced T regulatory cells and myeloid-derived suppressor cells expansion.
[Proceedings of the National Academy of Sciences of the United States of America]

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Abstract