Curcumin Mitigates TNFα-Induced Caco-2 Cell Monolayer Permeabilization through Modulation of NF-κB, ERK1/2 and JNK Pathways

Caco-2 cell monolayers were incubated with TNFα, in the absence or presence of curcumin. TNFα caused an increase in interleukin (IL)-6 and IL-8 release which was inhibited by curcumin in a dose-dependent manner