AHR Mediates the Aflatoxin B1 Toxicity Associated with Hepatocellular Carcinoma

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Aflatoxin exposure is a crucial factor in promoting the development of primary hepatocellular carcinoma in individuals infected with the hepatitis virus. AHR-deficient cells tolerated high concentrations of aflatoxin B1 (AFB1), in which AFB1 adduct formation was significantly decreased.
[Signal Transduction and Targeted Therapy]

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