Adipose Stem Cell Niche Reprograms the Colorectal Cancer Stem Cell Metastatic Machinery

By
Justin.choi
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Visceral adipose-derived factors promoted vasculogenesis and the onset of metastatic dissemination by activation of STAT3, which inhibited miR-200a and enhanced ZEB2 expression, effectively reprogramming colorectal cancer cells into a highly metastatic phenotype.
[Nature Communications]

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