Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell NewsThe cell-surface and subcellular biomarkers related to breast cancer stem cell (BCSC) phenotypes are increasingly being recognised. These biomarkers are useful for the isolation of BCSCs and can serve as potential therapeutic targets and prognostic tools to monitor treatment responses.
[Diagnostics ]
6445212 {6445212:TWILK5BH} apa 50 1 154443 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-b66a85d49439643192ced057b7ab8da1%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22TWILK5BH%22%2C%22library%22%3A%7B%22id%22%3A6445212%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ko%20et%20al.%22%2C%22parsedDate%22%3A%222020-09%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKo%2C%20C.%20C.%20H.%2C%20Chia%2C%20W.%20K.%2C%20Selvarajah%2C%20G.%20T.%2C%20Cheah%2C%20Y.%20K.%2C%20Wong%2C%20Y.%20P.%2C%20%26amp%3B%20Tan%2C%20G.%20C.%20%282020%29.%20The%20Role%20of%20Breast%20Cancer%20Stem%20Cell-Related%20Biomarkers%20as%20Prognostic%20Factors.%20%3Ci%3EDiagnostics%3C%5C%2Fi%3E%2C%20%3Ci%3E10%3C%5C%2Fi%3E%289%29%2C%20721.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fdiagnostics10090721%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fdiagnostics10090721%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445212%26amp%3Bitem_key%3DTWILK5BH%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Role%20of%20Breast%20Cancer%20Stem%20Cell-Related%20Biomarkers%20as%20Prognostic%20Factors%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clarence%20Ching%20Huat%22%2C%22lastName%22%3A%22Ko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wai%20Kit%22%2C%22lastName%22%3A%22Chia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gayathri%20Thevi%22%2C%22lastName%22%3A%22Selvarajah%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoke%20Kqueen%22%2C%22lastName%22%3A%22Cheah%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yin%20Ping%22%2C%22lastName%22%3A%22Wong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Geok%20Chin%22%2C%22lastName%22%3A%22Tan%22%7D%5D%2C%22abstractNote%22%3A%22Breast%20cancer%20is%20one%20of%20the%20leading%20causes%20of%20cancer-related%20deaths%20in%20women%20worldwide%2C%20and%20its%20incidence%20is%20on%20the%20rise.%20A%20small%20fraction%20of%20cancer%20stem%20cells%20was%20identified%20within%20the%20tumour%20bulk%2C%20which%20are%20regarded%20as%20cancer-initiating%20cells%2C%20possess%20self-renewal%20and%20propagation%20potential%2C%20and%20a%20key%20driver%20for%20tumour%20heterogeneity%20and%20disease%20progression.%20Cancer%20heterogeneity%20reduces%20the%20overall%20efficacy%20of%20chemotherapy%20and%20contributes%20to%20treatment%20failure%20and%20relapse.%20The%20cell-surface%20and%20subcellular%20biomarkers%20related%20to%20breast%20cancer%20stem%20cell%20%28BCSC%29%20phenotypes%20are%20increasingly%20being%20recognised.%20These%20biomarkers%20are%20useful%20for%20the%20isolation%20of%20BCSCs%20and%20can%20serve%20as%20potential%20therapeutic%20targets%20and%20prognostic%20tools%20to%20monitor%20treatment%20responses.%20Recently%2C%20the%20role%20of%20noncoding%20microRNAs%20%28miRNAs%29%20has%20extensively%20been%20explored%20as%20novel%20biomarker%20molecules%20for%20breast%20cancer%20diagnosis%20and%20prognosis%20with%20high%20specificity%20and%20sensitivity.%20An%20in-depth%20understanding%20of%20the%20biological%20roles%20of%20miRNA%20in%20breast%20carcinogenesis%20provides%20insights%20into%20the%20pathways%20of%20cancer%20development%20and%20its%20utility%20for%20disease%20prognostication.%20This%20review%20gives%20an%20overview%20of%20stem%20cells%2C%20highlights%20the%20biomarkers%20expressed%20in%20BCSCs%20and%20describes%20their%20potential%20role%20as%20prognostic%20indicators.%22%2C%22date%22%3A%222020%5C%2F9%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fdiagnostics10090721%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2075-4418%5C%2F10%5C%2F9%5C%2F721%22%2C%22deleted%22%3A1%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222020-09-23T20%3A14%3A55Z%22%7D%7D%5D%7D
Ko, C. C. H., Chia, W. K., Selvarajah, G. T., Cheah, Y. K., Wong, Y. P., & Tan, G. C. (2020). The Role of Breast Cancer Stem Cell-Related Biomarkers as Prognostic Factors. Diagnostics, 10(9), 721. https://doi.org/10.3390/diagnostics10090721 Cite
