Organoid-derived CD44(−) cancer cells were capable of organoid re-formation and could be re-programed as CD44-expressing cancer-initiating cells in the organoid culture system.
[Cancer Letters]
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Choi, J.-I., Jang, S. I., Hong, J., Kim, C. H., Kwon, S. S., Park, J. S., & Lim, J.-B. (2020). Cancer-initiating cells in human pancreatic cancer organoids are maintained by interactions with endothelial cells. Cancer Letters. https://doi.org/10.1016/j.canlet.2020.10.012 Cite