Generation of Patterned Kidney Organoids That Recapitulate the Adult Kidney Collecting Duct System from Expandable Ureteric Bud Progenitors

Researchers reported the generation of an expandable, 3D branching ureteric bud (UB) organoid culture model that could be derived from primary UB progenitors from mouse and human fetal kidneys, or generated de novo from human PSCs.