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Pulmonary Cell NewsScientists investigated whether interleukin 4 (IL4) had antileukemic activity via immune-mediated mechanisms in an in vivo murine model of acute myeloid leukemia driven by the MLL–AF9 fusion gene.
[Haematologica]
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Peña-Martínez, P., Ramakrishnan, R., Högberg, C., Jansson, C., Nord, D. G., & Järås, M. (2020). IL4 promotes phagocytosis of murine leukemia cells counteracted by CD47 upregulation. Haematologica. https://doi.org/10.3324/haematol.2020.270421 Cite
