LY-294002 Enhances the Chemosensitivity of Liver Cancer to Oxaliplatin by Blocking the PI3K/AKT/HIF-1α Pathway

By
Justin.choi
-
0
28
Scientists investigated the effects of the PI3K inhibitor LY‑294002 and AKT inhibitor MK2206 on the chemosensitivity of oxaliplatin‑resistant liver cancer cells and the molecular mechanism involved.
[Molecular Medicine Reports]
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Xu, R., Zhang, Y., Li, A., Ma, Y., Cai, W., Song, L., Xie, Y., Zhou, S., Cao, W., & Tang, X. (2021). LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathway. Molecular Medicine Reports, 24(1), 1–11. https://doi.org/10.3892/mmr.2021.12147 Cite
Abstract