Scientists showed that monocyte/macrophage CD11B mRNA levels were increased significantly in livers of biliary atresia patients and positively correlated with the progression of liver inflammation and fibrosis.
[Cell Death & Disease]
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Tian, X., Wang, Y., Lu, Y., Wang, W., Du, J., Chen, S., Zhou, H., Cai, W., & Xiao, Y. (2021). Conditional depletion of macrophages ameliorates cholestatic liver injury and fibrosis via lncRNA-H19. Cell Death & Disease, 12(7), 1–13. https://doi.org/10.1038/s41419-021-03931-1 Cite