A SNAI2-PEAK1-INHBA Stromal Axis Drives Progression and Lapatinib Resistance in HER2-Positive Breast Cancer by Supporting Subpopulations of Tumor Cells Positive for Antiapoptotic and Stress Signaling Markers

Mesenchymal stem cells and cancer-associated fibroblasts expressed high PEAK1 protein levels and potentiated tumorigenesis, lapatinib resistance and metastasis of HER2-positive breast cancer cells in a PEAK1-dependent manner.