Microvesicles Derived from Human Umbilical Cord Mesenchyme Promote M2 Macrophage Polarization and Ameliorate Renal Fibrosis Following Partial Nephrectomy via Hepatocyte Growth Factor

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Scientists investigated whether icrovesicles derived from human Wharton’s Jelly mesenchymal stromal cells regulated macrophage polarization and ameliorated renal fibrosis following ischemia-PN via transferring hepatocyte growth factor.
[Human Cell]
Du, T., Ju, G., Zhou, J., Zhong, L., Rong, L., Chen, W., Zhang, X., Zhou, R., Ding, D., & Ji, T. (2021). Microvesicles derived from human umbilical cord mesenchyme promote M2 macrophage polarization and ameliorate renal fibrosis following partial nephrectomy via hepatocyte growth factor. Human Cell. https://doi.org/10.1007/s13577-021-00525-z Cite
Abstract