3D imaging

[Scientific Reports] The authors used X-ray Phase Contrast Imaging to comprehensively quantify ischemic remodeling of different myocardial structures, from cell to organ level, in a rat model of myocardial infarction.

[Proceedings of the National Academy of Sciences of the United States of America] By using the xCell tool and the latest immunolabeling-enabled 3D imaging of solvent-cleared organs technique, we found severe pathological damage of the entire ENS and decreased expression of choline acetyltransferase in inflammatory bowel disease patients.

[Science Advances] Scientists performed 3D imaging of young and aging vascular beds. Multiple organs in mice and humans demonstrated an age-dependent decline in vessel density and pericyte numbers, while highly remodeling tissues such as skin preserve the vasculature.

[Frontiers in Bioengineering and Biotechnology] Scientists present a step-by-step methodology to generate human minibrain nurseries and novel strategies to subsequently label projection neurons, perform immunohistochemistry and 3D imaging of the minibrains at large multiplexable scales.

[EMBO Journal] Angiogenesis and β‐cell expansion in the pancreas were coupled by a distinct age‐dependent subset of endothelial cells (ECs). While this EC subpopulation supported pancreatic β cells, it declined during aging concomitant with increased expression of the gap junction protein Gja1.

[Scientific Reports] Scientists focused on defining extensive physical changes in chromatin organization in the process of skeletal myoblast differentiation.