cancer initiating cells

[Biochemical and Biophysical Research Communications] NRG1 is a trophic factor that contains an epidermal growth factor-like domain that signals by stimulating ERBB receptor tyrosine kinases and the cytoplasmic domain.

[Cells] Researchers investigatef whether Cisplatin, Imatinib, and 5-Fluorouracil alter the tumoroid growth of metastatic colorectal cancer.

[Cancer Letters] Organoid-derived CD44(−) cancer cells were capable of organoid re-formation and could be re-programed as CD44-expressing cancer-initiating cells in the organoid culture system.

[Diagnostics ] The cell-surface and subcellular biomarkers related to breast cancer stem cell (BCSC) phenotypes are increasingly being recognised. These biomarkers are useful for the isolation of BCSCs and can serve as potential therapeutic targets and prognostic tools to monitor treatment responses.

[British Journal of Cancer] Investigators developed a therapeutic single-chain variable-fragment antibody that recognises the cancer stem-like cell/cancer-initiating cell antigen, DNAJB8.