Investigators developed a therapeutic single-chain variable-fragment antibody that recognises the cancer stem-like cell/cancer-initiating cell antigen, DNAJB8.
[British Journal of Cancer]
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Tadano, H., Tsukahara, T., Mizushima, E., Akamatsu, A., Watanabe, K., Nojima, I., Kubo, T., Kanaseki, T., Hirohashi, Y., Sato, N., & Torigoe, T. (2020). Development of an artificial antibody specific for HLA/peptide complex derived from cancer stem-like cell/cancer-initiating cell antigen DNAJB8. British Journal of Cancer, 1–8. https://doi.org/10.1038/s41416-020-1017-1 Cite