macrophages

[Science Translational Medicine] Investigators showed that early-phase SARS-CoV-2 spike protein–specific immunoglobulin G (IgG) in serum of critically ill COVID-19 patients induces excessive inflammatory responses by human alveolar macrophages.

[Scientific Reports] Cross-sections from injured and non-injured human spinal cords were immunolabeled for α-synuclein. This showed robust α-synuclein accumulation in profiles resembling axons and astrocytes in tissue surrounding the injury, revealing that α-synuclein markedly aggregated in traumatically injured human spinal cords.

[Oncogene] The authors compared gene expression of growth factors in normal human nerves to malignant peripheral nerve sheath tumors (MPNST) and normal human Schwann cells to MPNST cell lines.

[Nature Reviews Molecular Cell Biology] The authors describe the mechanisms of tissue repair following damage, highlighting the close relationship between inflammation and liver regeneration, and discuss how recent findings can help design novel therapeutic approaches.

[Cell Death & Disease] Researchers investigated the survival and migration of MSC transplanted by various routes in order to identify the best delivery approach that provided an accumulation of therapeutic cells to the injured pancreas in the non-obese diabetic mouse.

[Cell Reports] Scientists characterized the metabolic and transcriptional responses of murine macrophages to Mycobacterium tuberculosis in order to disentangle the underlying mechanisms.