monocytes

[EMBO Journal] Investigators showed that the nucleocapsid of SARS-CoV-2 inhibited host pyroptosis by blocking Gasdermin D cleavage. SARS-CoV-2-infected monocytes showed enhanced cellular interleukin 1b (IL-1b) expression, but reduced IL-1b secretion.

[Scientific Reports] The authors used recently described RNA ligands for toll-like receptor (TLR)7 and TLR8 together with Vγ9Vδ2 T-cell specific pyrophosphate antigens to analyze the rapid cytokine induction in Vδ2 T cells as well as the accessory cell requirements.

[Scientific Reports] Researchers showed that Ly6G deficiency decreased the initial infection rate of neutrophils recruited to the site of skin infection.

[Bone Marrow Transplantation] Investigators evaluated the immune reconstitution of patients receiving omidubicel grafts during the first six months post-transplant, as IR is critical for favorable outcomes of the procedure.

[Circulation Research] The authors tested whether silencing netrin-1 in advanced atherosclerosis could resolve arterial inflammation and regress plaques.

[Scientific Reports] The authors found that the stimulation of human trabecular meshwork (TM) cells with monocyte chemoattractant protein (MCP)-1 and IL-8 induced significant increase in the formation of actin stress fibers and focal adhesions, myosin light chain phosphorylation, and the contraction of TM cells.