Monocyte-Dependent Co-stimulation of Cytokine Induction in Human γδ T Cells by TLR8 RNA Ligands

The authors used recently described RNA ligands for toll-like receptor (TLR)7 and TLR8 together with Vγ9Vδ2 T-cell specific pyrophosphate antigens to analyze the rapid cytokine induction in Vδ2 T cells as well as the accessory cell requirements.