Tag results:
myeloid cells
Hematopoiesis News
Deletion of Grin1 in Mouse Megakaryocytes Reveals NMDA Receptor Role in Platelet Function and Proplatelet Formation
[Blood] Researchers found that Pf4-Grin1-/- mice had defects in megakaryopoiesis, thrombopoiesis and platelet function, which manifested as reduced platelet counts, lower rates of platelet production in the immune model of thrombocytopenia, and a prolonged tail bleeding time.
Human Immunology News
S1P Analogues SEW2871, BAF312 and FTY720 Affect Human Th17 and Treg Generation Ex Vivo
[International Immunopharmacology] The authors investigated the effects of S1P receptor 1 (S1P1) specific S1P analogue SEW2871, S1P1 and S1P5 specific BAF312, and non-selective FTY720 on human Th17 and Treg differentiation and IL-23-mediated signaling.
Human Immunology News
Dendritic Cells a Critical Link to Alveolar Bone Loss and Systemic Disease Risk in Periodontitis: Immunotherapeutic Implications
[Periodontology 2000] Dendritic cells consist of multiple subsets that reside in the epithelium, connective tissues, and major organs.
Organoid News
Lactobacillus murinus Alleviate Intestinal Ischemia/Reperfusion Injury through Promoting the Release of Interleukin-10 from M2 Macrophages via Toll-Like Receptor 2 Signaling
[Microbiome] A transwell co-culture system of small intestinal organoids extracted from control mice and macrophages extracted from control mice or Toll-like receptor 2 (TLR2)-deficient mice or IL-10-deficient mice were established separately to explore the potential mechanism of reducing intestinal ischemia/reperfusion injury.
Immune Regulation News
Differential Impact of JUUL Flavors on Pulmonary Immune Modulation and Oxidative Stress Responses in Male and Female Mice
[Archives of Toxicology] The author discusses the increase in circulating follicular helper T cells seen in autoimmune settings and explores potential explanations for this phenomenon.
Immune Regulation News
Macrophage Compartmentalization in the Brain and Cerebrospinal Fluid System
[Science Immunology] The authors review the relationships between central nervous system macrophage populations, with a focus on the origins, phenotypes, and functions of cerebrospinal fluid macrophages in health and disease.