squamous cell carcinoma

[Cancer Cell International] The effects of conditioned media from oral squamous cell carcinoma cells on the angiogenic activities of endothelial cells were analyzed using a tube formation assay.

[Cell Death & Disease] Researchers showed that high LSD1 expression was a predictor of poor prognosis for head and neck squamous cell carcinoma patients. They found that high expression of LSD1 was essential for the maintenance of the CSC properties by regulating Bmi-1 expression.

[Cell Death & Disease] Cancer stem-like cells drive tumorigenesis and progression of head and neck squamous cell carcinoma (HNSCC). Scientists observed that high Bmi-1 expression correlated with decreased recurrence-free survival time in HNSCC patients

[Oncogene] The long non-coding RNA, HOX antisense intergenic RNA (HOTAIR), is a well-characterized oncogene in multiple human cancers, but not in cutaneous squamous cell carcinoma (CSCC). In this study, researchers investigated the potential role of HOTAIR in the stemness of CSCC.

[Scientific Reports] Secondary cisplatin resistance majorly undermines the cisplatin efficacy leading to a worse prognosis. In this respect, researchers identified the role of the DLX6-AS1/miR-181a-5p/miR-382-5p/CELF1 axis in regulating cisplatin resistance of lung squamous cell carcinoma.

[Cell Death & Disease] Researchers demonstrated that kinectin1 knockdown induced epidermal growth factor receptor (EGFR) degradation in cutaneous squamous cell carcinoma cells and promoted the ubiquitin-proteasome system, and that this effect was tumor cell-specific.