Independent Evolution of Cutaneous Lymphoma Subclones in Different Microenvironments of the Skin

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By sequencing the exomes of the microdissected clusters of lymphoma cells from the epidermis and the dermis, scientists found that those microenvironments comprised different malignant clonotypes.
[Scientific Reports]
Iyer, A., Hennessey, D., O’Keefe, S., Patterson, J., Wang, W., Wong, G. K.-S., & Gniadecki, R. (2020). Independent evolution of cutaneous lymphoma subclones in different microenvironments of the skin. Scientific Reports, 10(1), 15483. https://doi.org/10.1038/s41598-020-72459-9 Cite
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