On the Road Again – Establishment and Maintenance of Stemness in the Neural Crest from Embryo to Adulthood

The neural crest (NC) is an ESC population that contributes to a greatly expanding list of derivatives ranging from neurons and glia of the peripheral nervous system, facial cartilage and bone, pigment cells of the skin to secretory cells of the endocrine system. Scientists focus on what is specifically known about establishment and maintenance of NC stemness and ultimate fate commitment mechanisms.