Homeostatic and Early-Recruited CD101− Eosinophils Suppress Endotoxin-Induced Acute Lung Injury

By
Justin.choi
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0
5
Blood eosinophils were increased in surviving patients with acute respiratory distress syndrome (ARDS) independent of corticosteroid usage. There existed homeostatic eosinophils in lung parenchyma in mice and these homeostatic eosinophils, originating from the bone marrow, were predominantly CD101−.
[European Respiratory Journal]
Zhu, C., Weng, Q.-Y., Zhou, L.-R., Cao, C., Li, F., Wu, Y.-F., Wu, Y.-P., Li, M., Hu, Y., Shen, J.-X., Xiong, X.-F., Lan, F., Xia, L.-X., Zhang, B., Zhang, H., Huang, M., Ying, S.-M., Shen, H.-H., Chen, Z.-H., & Li, W. (2020). Homeostatic and early-recruited CD101− eosinophils suppress endotoxin-induced acute lung injury. European Respiratory Journal, 56(5). https://doi.org/10.1183/13993003.02354-2019 Cite
Abstract