MALAT1 Maintains the Intestinal Mucosal Homeostasis in Crohn’s Disease via the miR-146b-5p-CLDN11/NUMB Pathway

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Effects of intestinal epithelial cells transfected with metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) lentiviruses and Smart Silencer, on monolayer permeability and apical junction complex proteins were analyzed.
[Journal of Crohns & Colitis]
Li, Y., Zhu, L., Chen, P., Wang, Y., Yang, G., Zhou, G., Li, L., Feng, R., Qiu, Y., Han, J., Chen, B., He, Y., Zeng, Z., Chen, M., & Zhang, S. (2021). MALAT1 maintains the intestinal mucosal homeostasis in Crohn’s disease via the miR-146b-5p-CLDN11/NUMB pathway. Journal of Crohn’s and Colitis, jjab040. https://doi.org/10.1093/ecco-jcc/jjab040 Cite
Abstract