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Pulmonary Cell NewsResearchers showed that the CNS-endogenous hedgehog pathway attenuated the pathogenicity of human and mouse effector CD4 T cells by regulating their production of inflammatory cytokines.
[Brain]
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Benallegue, N., Kebir, H., Kapoor, R., Crockett, A., Li, C., Cheslow, L., Abdel-Hakeem, M. S., Gesualdi, J., Miller, M. C., Wherry, E. J., Church, M. E., Blanco, M. A., & Alvarez, J. I. (2021). The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation. Brain, awab083. https://doi.org/10.1093/brain/awab083 Cite
