Exosomal miR-106b-5p Derived from Melanoma Cell Promotes Primary Melanocytes Epithelial-Mesenchymal Transition through Targeting EphA4

miR-106b-5p was enriched in melanoma cell-secreted exosomes and transferred to melanocytes. Exosomal miR-106b-5p promoted the epithelial-to-mesenchymal transition, migration, invasion and adhesion of melanocytes. Exosomal miR-106b-5p exerted its role by targeting erythropoietin-producing hepatocellular carcinoma receptor A4 (EphA4) to activate the ERK pathway.