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Pulmonary Cell NewsScientists report that a p300/CBP inhibitor, A-485, could overcome resistance to idelalisib in mantle cell lymphoma cells in vitro and in vivo.
[Acta Pharmacologica Sinica]
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Zhou, X., Li, X., Liao, L., Han, J., Huang, J., Li, J., Tao, H., Fan, S., Chen, Z., Li, Q., Chen, S., Ding, H., Yang, Y., Zhou, B., Jiang, H., Chen, K., Zhang, Y., Huang, C., & Luo, C. (2021). P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib. Acta Pharmacologica Sinica, 1–13. https://doi.org/10.1038/s41401-021-00643-2 Cite
