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Pulmonary Cell NewsThe authors describe the functional roles of the bone microenvironment and its components in the initiation and propagation of skeletal metastases, outline the biology and clinical relevance of circulating tumor cells and disseminated tumor cells, and discuss established and future therapeutic approaches that specifically target defined components of the bone microenvironment to prevent or treat skeletal metastases.
[Nature Reviews Clinical Oncology]
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Hofbauer, L. C., Bozec, A., Rauner, M., Jakob, F., Perner, S., & Pantel, K. (2021). Novel approaches to target the microenvironment of bone metastasis. Nature Reviews Clinical Oncology, 1–18. https://doi.org/10.1038/s41571-021-00499-9 Cite
