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Pulmonary Cell NewsThe apoptotic loss of dendritic spines would be aggravated by microglia activation through a recently described signaling system from complement abnormalities and proteins of the MHC, thus implicating the immune system in schizophrenia.
[Translational Psychiatry]
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Parellada, E., & Gassó, P. (2021). Glutamate and microglia activation as a driver of dendritic apoptosis: a core pathophysiological mechanism to understand schizophrenia. Translational Psychiatry, 11(1), 1–13. https://doi.org/10.1038/s41398-021-01385-9 Cite
