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Pulmonary Cell NewsThe authors showed that CD4+ T cells from patients with psoriasis and psoriatic arthritis exhibit increased production of IL-17 but decreased expression of IL-2 and PD-1.
[Journal of Immunology]
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Hofmann, S. R., Carlsson, E., Kapplusch, F., Carvalho, A. L., Liloglou, T., Schulze, F., Abraham, S., Northey, S., Russ, S., Surace, A. E. A., Yoshida, N., Tsokos, G. C., & Hedrich, C. M. (2021). Cyclic AMP Response Element Modulator-α Suppresses PD-1 Expression and Promotes Effector CD4+ T Cells in Psoriasis. The Journal of Immunology. https://doi.org/10.4049/jimmunol.2100240 Cite
