Influenza Virus Infection Expands the Breadth of Antibody Responses through IL-4 Signaling in B Cells

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Justin.choi
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Researchers showed that nasal infection controls two sequential processes to induce neutralizing IgG antibodies recognizing the hemagglutinin (HA) of heterotypic strains.
[Nature Communications]
Miyauchi, K., Adachi, Y., Tonouchi, K., Yajima, T., Harada, Y., Fukuyama, H., Deno, S., Iwakura, Y., Yoshimura, A., Hasegawa, H., Yugi, K., Fujii, S., Ohara, O., Takahashi, Y., & Kubo, M. (2021). Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells. Nature Communications, 12(1), 3789. https://doi.org/10.1038/s41467-021-24090-z Cite
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