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Pulmonary Cell NewsScientists identified genomic contexts in which neuroendocrine transformation was favored, including frequent loss of the 3p chromosome arm.
[Cancer Discovery]
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Quintanal-Villalonga, A., Taniguchi, H., Zhan, Y. A., Hasan, M. M., Chavan, S. S., Meng, F., Uddin, F., Manoj, P., Donoghue, M. T. A., Won, H. H., Chan, J. M., Ciampricotti, M., Chow, A., Offin, M., Chang, J. C., Ray-Kirton, J., Tischfield, S. E., Egger, J., Bhanot, U. K., … Sen, T. (2021). Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation. Cancer Discovery. https://doi.org/10.1158/2159-8290.CD-20-1863 Cite
