Ferroportin downregulation in hepatic cells increased the levels of the M2 markers CD206, TGF- β, VEGF, MMP-9, Laminin, Collagen, IL-4 and IL-10.
[Scientific Reports]
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Cai, C., Zeng, D., Gao, Q., Ma, L., Zeng, B., Zhou, Y., & Wang, H. (2021). Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis. Scientific Reports, 11(1), 13386. https://doi.org/10.1038/s41598-021-92839-z Cite