Structure-Guided T Cell Vaccine Design for SARS-CoV-2 Variants and Sarbecoviruses

By
Justin.choi
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0
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Investigators applied structure-based network analysis and assessments of HLA class I-peptide stability to define mutationally constrained CD8+ T cell epitopes across the SARS-CoV-2 proteome.
[Cell]
Nathan, A., Rossin, E. J., Kaseke, C., Park, R. J., Khatri, A., Koundakjian, D., Urbach, J. M., Singh, N. K., Bashirova, A., Tano-Menka, R., Senjobe, F., Waring, M. T., Piechocka-Trocha, A., Garcia-Beltran, W. F., Iafrate, A. J., Naranbhai, V., Carrington, M., Walker, B. D., & Gaiha, G. D. (2021). Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses. Cell, 0(0). https://doi.org/10.1016/j.cell.2021.06.029 Cite
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