Phase III Randomized Trial of Chemotherapy with or without Oblimersen in Older AML Patients: CALGB 10201 (Alliance)

Untreated older acute myeloid leukemia (AML) patients were randomized to cytarabine and daunorubicin followed by cytarabine consolidation with or without G3139. Addition of G3139 to chemotherapy failed to improve outcomes of older AML patients.