DJ-1 Inhibits Microglial Activation and Protects Dopaminergic Neurons In Vitro and In Vivo through Interacting with Microglial p65

Pharmacological blockage of NF-κB nuclear translocation by SN-50 prevented microglial activation and alleviated the damage of dopaminergic neurons induced by microglial DJ-1 deficiency in vivo and in vitro.