DNAJA1 Dysregulates Metabolism Promoting an Antiapoptotic Phenotype in Pancreatic Ductal Adenocarcinoma

The impact of DNAJA1 expression on pancreatic ductal adenocarcinoma progression remains unclear. The metabolic impacts of increased DNAJA1 expression were evaluated using a combination of untargeted metabolomics, stable isotope-resolved metabolomics, confocal microscopy, flow cytometry, and cell-based assays.