CIAPIN1 Accelerates Vascular Remodelling via p53 and JAK2-STAT3 Regulation in Vascular Smooth Muscle Cells

Researchers used loss/gain-of-function approaches by gene delivery to determine whether cytokine induced apoptosis inhibitor 1 (CIAPIN1) modulated vascular smooth muscle cell proliferation, migration, and neointima formation, and to define the underlying mechanisms.