Using mice specifically defective for either mTORC1 or mTORC2 in ILC3s, scientists show that both mTOR complexes regulate the maintenance of type III Innate lymphoid cells at steady state and pathological immune response during colitis.
[Mucosal Immunology]
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Teufel, C., Horvath, E., Peter, A., Ercan, C., Piscuoglio, S., Hall, M. N., Finke, D., & Lehmann, F. M. (2021). mTOR signaling mediates ILC3-driven immunopathology. Mucosal Immunology, 1–12. https://doi.org/10.1038/s41385-021-00432-4 Cite