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Pulmonary Cell NewsPeripheral blood endothelial progenitor cells were isolated from nonsmoking non-chronic obstructive pulmonary disease (COPD), smoking non-COPD, and smoking COPD patients. The expressions of p16, p300, and senescence-related genes were detected by RT-PCR and Western Blot.
[Mediators of Inflammation]
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He, Z., Peng, H., Gao, M., Liang, G., Zeng, M., & Zhang, X. (2021). p300/Sp1-Mediated High Expression of p16 Promotes Endothelial Progenitor Cell Senescence Leading to the Occurrence of Chronic Obstructive Pulmonary Disease. Mediators of Inflammation, 2021, e5599364. https://doi.org/10.1155/2021/5599364 Cite
