Circ_0004018 Suppresses Cell Proliferation and Migration in Hepatocellular Carcinoma via miR-1197/PTEN/PI3K/AKT Signaling Pathway

Researchers conducted quantitative reverse transcription PCR to find that circ_0004018 was down-regulated in hepatocellular carcinoma cells. Western blot analysis was performed to detect the protein levels of phosphatase and tensin homologue and related factors of PI3K/AKT signaling pathway.